Salivary phosphorus binding: a novel approach to control hyperphosphatemia.
نویسنده
چکیده
BASIC RESEARCH 495 CD36 Regulates Oxidative Stress and Inflammation in Hypercholesterolemic CKD Daryl M. Okamura, Subramaniam Pennathur, Katie Pasichnyk, Jesús M. López-Guisa, Sarah Collins, Maria Febbraio, Jay Heinecke, and Allison A. Eddy 506 Connexin Expression in Renin-Producing Cells Lisa Kurtz, Ulrike Janssen-Bienhold, Armin Kurtz, and Charlotte Wagner 513 Epoxyeicosatrienoic Acid Activates BK Channels in the Cortical Collecting Duct Peng Sun, Wen Liu, Dao-Hong Lin, Peng Yue, Rowena Kemp, Lisa M. Satlin, and Wen-Hui Wang JASNMarch 2009 Vol. 20 No. 3
منابع مشابه
Phosphate salivary secretion in hemodialysis patients: implications for the treatment of hyperphosphatemia.
BACKGROUND/AIMS Hyperphosphatemia is recognized as contributing to the increased risk of cardiac death in end-stage renal disease (ESRD) and hemodialysis (HD) patients. Currently available pharmacologic treatment for hyperphosphatemia is based on phosphate binders but, despite treatment, only half of the patients fall within the range for serum phosphorus of the K/DOQI guidelines. Therefore, th...
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BACKGROUND HS219 (40 mg chitosan-loaded chewing gum) is designed to bind salivary phosphorus as an add-on to available phosphorus binders. We performed a randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of HS219 in hemodialysis (HD) patients with hyperphosphatemia as an add-on to phosphorus binders. METHODS Sixty-eight HD patients who were maintained on c...
متن کاملSalivary phosphate secretion in chronic kidney disease.
BACKGROUND Hyperphosphatemia is an important contributor to cardiovascular calcification in chronic renal failure (CRF) patients. Cardiovascular calcifications are responsible for the high morbidity and mortality in patients undergoing hemodialysis (HD). Despite dietary phosphate reduction and treatment with phosphate binders, serum phosphorus level, as recommended by K/DOQI guidelines, is achi...
متن کاملSalivary phosphorus and phosphate content of beverages: implications for the treatment of uremic hyperphosphatemia.
BACKGROUND Hyperphosphatemia provides relevant and dangerous evidence of end-stage renal disease (ESRD) in patients undergoing periodic hemodialysis. The relationship between hyperphosphatemia and cardiovascular calcification, with the consequences of high morbidity and mortality after cardiovascular events, is well-defined. Hyperphosphatemia is treated by dietary limitation of phosphorus inges...
متن کاملارزیابی کلسیم، فسفر و پتاسیم بزاق و بررسی ارتباط آن‌ها با فاکتورهای بیوشیمیایی خون در بیماران همودیالیزی
Background: Nowadays, chronic kidney disease (CKD) is known as an epidemic disease all around the world. Chronic kidney disease considered as a serious health problem with numerous side effects, including complications progressive in reducing glomerular filtration rate (GFR), imbalances in the homeostasis of the body and decreased quality of life and finally an increase in mortality due to card...
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ورودعنوان ژورنال:
- Journal of the American Society of Nephrology : JASN
دوره 20 3 شماره
صفحات -
تاریخ انتشار 2009